Adverse Cases
The long and the short of movement disorders with metoclopramide
Isotretinoin and acquired hearing impairment
Is it leflunomide lung?
Fixed drug eruptions
Serotonin syndrome with duloxetine
Fentanyl transdermal patches and accidental child exposure
Intravitreal injection of triamcinolone acetonide: ocular reactions
Montelukast (Singulair): psychiatric reactions
Metformin, dehydration and lactic acidosis
Drug-induced lupus erythematosus: An emerging association with TNF inhibitors
Drug-associated macular oedema - latanoprost and rosiglitazone
Lignocaine with chlorhexidine gel and anaphylaxis
Serious reaction reminders: cefaclor and serum sickness-like reactions in children
Serious reaction reminders: sodium valproate and fetal malformations
Severe adverse reactions with intravenous immunoglobulin
Proton pump inhibitors and possible fracture risk
Adverse reactions with botulinum toxin A (Botox, Dysport)
More Data Support Adverse Clopidogrel and PPI Interaction
Risks of fulminant liver failure when stopping drugs for the management of hepatitis B
Modafinil: adverse skin and psychiatric reactions
Varenicline: The Australian experience so far
Drug-induced hyponatraemia
Fluoroquinolone antibiotics and tendon disorders: still a problem
Fatal interactions and reactions with colchicine: beware CYP3A4 inhibitors
Desmopressin and hyponatraemia
High-dose vitamin B6 may cause peripheral neuropathy
Hepatic toxicity with nitrofurantoin
Statins and muscle disorders – be careful with the dose
Topiramate and other drugs causing glaucoma
Nicorandil-associated ulceration
MRI scans with gadolinium-containing contrast agents and the risk of NSF – caution in patients with renal impairment
Hepatic reactions with terbinafine
Interaction between glucosamine and warfarin
Transdermal medications - look for the patch
Reports of hypersensitivity reactions to pregabalin
Erythropoietins: aim for lower haemoglobin levels
Emerging cardiovascular concerns with rosiglitazone
Dangers associated with chronic ingestion of colloidal silver
Renal impairment with zoledronic acid
Thiazolidinediones and reduced bone density
Atypical antipsychotic agents and extrapyramidal side effects
Implanon: interactions and failure of contraception
Rituximab and progressive multifocal leukoencephalopathy
Black cohosh and liver toxicity – an update
Mirtazapine and blood dyscrasias
Clozapine and myocarditis
Aripiprazole and neuroleptic malignant syndrome
Zolpidem and bizarre sleep related effects
Traditional Indian (Ayurvedic) and Chinese medicines associated with heavy metal poisoning
Increased risk of fractures associated with enzyme-inducing antiepileptic medicines
Green tea extract (Green Lite): suspected association with hepatotoxicity
Domperidone: heart rate and rhythm disorders
Levofloxacin: dysglycemia and liver disorders
Tumour necrosis factor alpha inhibitors
Leflunomide and interstitial lung disease
Drug induced pancreatitis
Ezetimibe and depression - A possible signal
Leflunomide and peripheral neuropathy
Beware the triple whammy!
Life threatening blood dyscrasias with oral terbinafine
Dose reduction of LMWH (enoxaparin) in chronic kidney disease
Osteonecrosis of the jaw with bisphosphonates
Interactions with macrolides
Hepatotoxicity with black cohosh
Fluoroquinolone antibiotics ...Remember tendon disorders
Fluoroquinolone antibiotics ...Interactions with warfarin
Deaths with galantamine in mild cognitive impairment studies
Warfarin-induced skin necrosis
Skin reactions with glucosamine
Medicines and QT prolongation
Inadvertent paracetamol overdose
Pathological gambling with cabergoline
Ezetimibe and muscle disorders
Suicidality with SSRIs: adults and children
The multiple toxicities of amiodarone
Genitourinary symptoms with reboxetine
Evidence-based medicine: pitfalls of overlooking safety
Angioedema - still a problem with ACE inhibitors
Avascular necrosis with interferon alfa-2b in CML
Statins and peripheral neuropathy
Statins contraindicated in pregnancy
Adverse reactions to complementary medicines
Propofol: danger of prolonged and high infusion rates in ICU
Cholinesterase inhibitors and cardiac arrhythmias
Terbinafine and blood dyscrasias
Acute neuropsychiatric events with celecoxib and rofecoxib
Tramadol and serotonin syndrome
Seeing things with zolpidem
Interaction of rofecoxib with warfarin
Amiodarone and pulmonary toxicity
Electrolyte Disturbances With Sodium Picosulfate Bowel Cleansing Products
Severe skin reactions and venous thromboembolism with strontium ranelate (Protos)
Venous thromboembolism with third generation oral contraceptives and cyproterone
Haemorrhagic cystitis with ticarcillin in cystic fibrosis patients
Sildenafil - Three Years Experience
Indapamide and hyponatraemia
Pulmonary toxicity with long-term nitrofurantoin
Quinine and profound thrombocytopenia
Patent blue V and anaphylaxis
Miconazole oral gel elevates INR - a reminder
Fluoroquinolones and tendon disorders
Interactions with grapefruit juice
Fluticasone and adrenal crisis
Hepatic reactions with minocycline
Paroxetine not safe for children, an increase in the rate of self-harm and potentially suicidal behaviours reported
ACE inhibitor, diuretic and NSAID: a dangerous combination
Maternal SSRI use and neonatal effects
Serious gastrointestinal effects with celecoxib and rofecoxib
Spironolactone + ACE inhibitor Interactions
Clarithromycin + digoxin Interactions
Trimethoprim/sulphamethoxazole+glibenclamide Interactions
Serotonin syndrome
High dose cyproterone and hepatotoxicity
Risk factors for myopathy and rhabdomyolysis with the statins
Bisphosphonates and ocular inflammation
Macrolides and warfarin interaction
The risks and benefits of HRT
